Swollen syndrome different Genesis (heart, liver, kidney after the second month of pregnancy, intoxication), pulmonary edema and brain, blood pressure, forced diuresis, renal failure.
Hypersensitivity (including to other sulfon - and sulfanilamide), acute glomerulonephritis, renal failure with anuria, hepatic coma, impaired water-salt balance and acid-base balance (hypokalemia, hyponatremia).
Application of pregnancy and breastfeeding
If pregnant, use under strict indications and only for a short time. At the time of treatment breastfeeding should be suspended.
Hypotension, dry mouth, arrhythmia,nausea, diarrhea,vomiting, pancreatitis, dehydration, hypovolemia, hypokalemia, gipohloremia, hyponatremia,metabolic alkalosis, hyperuricemia, hypocalcemia,dermatitis, vision, impaired hearing, paresthesia, muscle weakness,dizziness, urinary retention in patients with BPH, hypertriglyceridemia,hypercholesterolemia, reduced tolerance to glucose, allergic reaction (rash, fever, vasculitis, interstitial nephritis); acute pancreatitis,in preterm children nephrocalcinosis.
Method of application and doses
Inside, are usually prescribed on an empty stomach; in/enter for at least 1-2 min. With mild edematous syndrome the initial dose for adults is 20-80 mg when administered 20-40 mg in/in; in the case of persistent swelling is the same or increasing to 20-40 mg (20 mg for parenteral administration), the dose may be reappointed not earlier than in 6-8 hours (2 hours for parenteral administration) until the receipt of diuretic effect; such an individualized dosage can be used 1 or 2 times a day. The highest efficiency is achieved when taking the drug 2-4 days a week. For children initial dose — 2 mg/kg of body weight (for parenteral introduction of 1 mg/kg), with a poor effect can be increased by 1-2 mg/kg (parenteral 1 mg/kg), but not earlier than 6-8 hours (for parenteral administration, this period is not less than 2 h). When arterial hypertension initial dose for adults — 80 mg / day in 2 admission. Pulmonary edema Lasix is injected in/in the dose of 40 mg, if necessary, after 20 min, the introduction of the drug in the dose of from 20 to 40 mg.