The testimony of the drug Nolvadex
Hot flashes, vaginal bleeding, endometrial hyperplasia, vulvar itching, diarrhoeal disorders, dizziness, water retention in the body, hypercalcemia, thrombocytopenia, alopecia, uterine fibroids, leukopenia, thromboembolism.
Potentiates the effect of anticoagulants. In combination with cytotoxic means possible thromboembolic complications.
Method of application and doses
Inside, in breast cancer — 20-40 mg/day (for 1 or 2 admission).
Rapidly absorbed, for 4-7 hours it creates the maximum concentration in the blood. Equilibrium concentration (300 ng/mg) is achieved at a daily dose of 40 mg for 4 weeks. 99% bound to albumin. Metabolized, is excreted in the faeces, the half-life of tamoxifen for 7 days, X-desmethyltamoxifen (the major metabolite) to 14 days.
The composition and form of issue
1 tablet coated liner contains tamoxifen (citrate) 10 or 20 mg