Nolvadex

From 0.5 USD

Description

Nolvadex belongs to the class of anti-estrogens. The medicine is prescribed for breast cancer treatment.

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The testimony of the drug Nolvadex

Breast cancer.

Side effects

Hot flashes, vaginal bleeding, endometrial hyperplasia, vulvar itching, diarrhoeal disorders, dizziness, water retention in the body, hypercalcemia, thrombocytopenia, alopecia, uterine fibroids, leukopenia, thromboembolism.

Interaction

Potentiates the effect of anticoagulants. In combination with cytotoxic means possible thromboembolic complications.

Method of application and doses

Inside, in breast cancer — 20-40 mg/day (for 1 or 2 admission).

Clinical pharmacology

Rapidly absorbed, for 4-7 hours it creates the maximum concentration in the blood. Equilibrium concentration (300 ng/mg) is achieved at a daily dose of 40 mg for 4 weeks. 99% bound to albumin. Metabolized, is excreted in the faeces, the half-life of tamoxifen for 7 days, X-desmethyltamoxifen (the major metabolite) to 14 days.

The composition and form of issue

1 tablet coated liner contains tamoxifen (citrate) 10 or 20 mg