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Metformin activates AMP-activated protein kinase which affects p53 function. Two earlier observational studies have shown that diabetics who take have a lower rate of cancer incidence and mortality than other diabetics. ...
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Diabetes drug metformin shows promise as a cancer drug
Filed under: ResearchA new study reported in Cancer Research shows that a common diabetes drug, metformin, kills human tumor cells in mice that lack p53, a key regulatory gene. In more than half of all human cancers, the p53 gene has ...
